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1. - depolarization 2. inside of cell positive - depolarization 3. an increase in extracellular concentration of - .
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leak in neuronal excitability and Dejian Ren 1 Affiliation 1 of Biology, University of Pennsylvania, PA , USA. dren@ DOI: / Abstract.
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a passage, cut, or groove can pass or flow across a solid structure. a slow voltage .
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include bacterial voltage-gated Na + (Na V Bac) (Ren et al., b), bacterial putative voltage-gated Ca 2+ (Ca V Bac), and Ca 2+ (CatSpers) are found in vertebrates and invertebrates and, in are localized to and required for fertility (Ren and Xia, ).
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are two classes of in voltage-gated (VGSC) and (ESC). generic.
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DOI: Abstract Uterine contractions are regulated by electrical activity of cells .
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NALCN is an in and aspects of gating, ion selectivity and obscure. we investigate .
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we investigate essential leak and structure of NALCN in a distinct auxiliary subunit, sequence A an extracellular ion-selectivity filter neurotoxin attack.
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of resting potential is presence of K+ leak in cellular does contain Na+ leak allow Na+ to return to cell, but are found in far fewer K+ leak a ratio).
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leak (NALCN), a non-selective cation background Na + leak conductance and controls neuronal excitability and .
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leak (NALCN), a non-selective background leak cation is widely expressed in nervous including DRG and spinal cord (Lu et al., ; et al., ). NALCN can regulate neuronal resting potential Lu et al., ; et al., ), is associated neuronal.
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Persistently depolarizing (Na +) leak currents electrical excitability 1, 2. ion NALCN represents a distinct of DI–DIV, six ion Function.
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in Nalcn, Unc79, or Unc80 lead to severe include neonatal and disruption in review discusses properties of NALCN its regulation, and its.
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